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Integration-free Methods for Generating Induced Pluripotent Stem Cells

โœ Scribed by Zhou, Yi-ye; Zeng, Fanyi


Book ID
122156485
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
295 KB
Volume
11
Category
Article
ISSN
1672-0229

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Induced pluripotent stem cells generated
โœ Reto Eggenschwiler; Tobias Cantz ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 132 KB ๐Ÿ‘ 1 views

Pluripotent stem cells have been generated from mouse and human somatic cells by viral expression of the transcription factors Oct4, Sox2, Klf4, and c-Myc. A major limitation of this technology is the use of potentially harmful genome-integrating viruses. Here, we generate mouse induced pluripotent