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Integrating the oral fluoropyrimidines into the management of advanced colorectal cancer

โœ Scribed by D Cunningham; R.D James


Book ID
117657181
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
170 KB
Volume
37
Category
Article
ISSN
0959-8049

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Capecitabine, a new oral fluoropyrimidin
โœ Francesco Di Costanzo; Andrea Sdrobolini; Silvia Gasperoni ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 200 KB

Capecitabine (Xeloda) ยฎ was developed as a tumour-selective fluoropyrimidine carbamate to achieve higher intratumoural 5-FU level and lower toxicity than 5-FU. Capecitabine passes unchanged through the gastrointestinal tract and is metabolised in the liver to 5%-deoxy-5-fluorocytidine (5%-DFCR). Her