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Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

✍ Scribed by Tabas, Ira; Ron, David


Book ID
109911459
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
232 KB
Volume
13
Category
Article
ISSN
1465-7392

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## Abstract Interferon‐γ (IFN‐γ) induces cell‐cycle arrest and p53‐independent apoptosis in primary cultured hepatocytes. However, the detailed mechanism, including regulating molecules, is still unclear. In this study, we found that IFN‐γ induced generation of reactive oxygen species (ROS) in prim