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Insulin stimulates some initial events necessary for the initiation of DNA replication in Swiss 3T3 cells

โœ Scribed by DEASUA, L; SMITH, C; OTTO, A

Book ID
122281674
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
411 KB
Volume
6
Category
Article
ISSN
0309-1651

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The stimulation of the initiation of DNA
The stimulation of the initiation of DNA synthesis by fibroblast growth factor in swiss 3T3 cells: Interactions with hormones during the pre-replicative phase
โœ K. M. Veronica Richmond; Anne-Marie Kubler; Francisco Martin; Luis Jimenez De As ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 637 KB

Fibroblast Growth Factor (FGF) stimulates quiescent Swiss 3T3 cells to initiate DNA synthesis and divide. Cells begin to enter the S-phase after a lag of 13-15 hr, and the rate of initiation of DNA synthesis in the population can be quantified by a first order rate constant, k. A subsaturating conce