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Inorganic phosphate is necessary for the stimulation of DNA synthesis in swiss 3T3 cells by pure mitogenic agents

โœ Scribed by Michael A. Becker; Enrique Rozengurt


Book ID
115891576
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
525 KB
Volume
139
Category
Article
ISSN
0014-4827

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The stimulation of the initiation of DNA
โœ K. M. Veronica Richmond; Anne-Marie Kubler; Francisco Martin; Luis Jimenez De As ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 637 KB

Fibroblast Growth Factor (FGF) stimulates quiescent Swiss 3T3 cells to initiate DNA synthesis and divide. Cells begin to enter the S-phase after a lag of 13-15 hr, and the rate of initiation of DNA synthesis in the population can be quantified by a first order rate constant, k. A subsaturating conce