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Insulin Receptor Splicing Alteration in Myotonic Dystrophy Type 2

โœ Scribed by R.S. Savkur; A.V. Philips; T.A. Cooper; J.C. Dalton; M.L. Moseley; L.P.W. Ranum; J.W. Day


Book ID
117854457
Publisher
American Society of Human Genetics
Year
2004
Tongue
English
Weight
323 KB
Volume
74
Category
Article
ISSN
0002-9297

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## Abstract Myotonic dystrophy type1 (DM1) is a multisystemic disorder caused by a CTG repeat expansion in the __DMPK__ gene. Aberrant mRNA splicing of several genes has been reported to contribute to some of the symptoms, including myotonia and insulin resistance, but the cause of muscle wasting i