Altered mRNA splicing of dystrophin in t
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Masayuki Nakamori; Takashi Kimura; Harutoshi Fujimura; Masanori P. Takahashi; Sa
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Article
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2007
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John Wiley and Sons
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English
β 180 KB
## Abstract Myotonic dystrophy type1 (DM1) is a multisystemic disorder caused by a CTG repeat expansion in the __DMPK__ gene. Aberrant mRNA splicing of several genes has been reported to contribute to some of the symptoms, including myotonia and insulin resistance, but the cause of muscle wasting i