Insulin-like growth factors in human breast cancer
β Scribed by Matthew J. Ellis; Sara Jenkins; John Hanfelt; Maura E. Redington; Marian Taylor; Russel Leek; Ken Siddle; Adrian Harris
- Book ID
- 110232354
- Publisher
- Springer US
- Year
- 1998
- Tongue
- English
- Weight
- 639 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0167-6806
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π SIMILAR VOLUMES
In the current study the authors have investigated whether human primary breast cancer specimens contain insulin-like growth factor-1 (IGF-1) receptors (IGF-1-R) or IGF-1-like activities. Simultaneously, epidermal growth factor (EGF) receptors (EGF-R) and cytosolic estrogen receptor (ER), progestero
The insulin-like growth factors (IGFs) have been implicated in the growth regulation of human breast cancer. Since the lCFs are associated with specific binding proteins (ICFBPs) which may modulate receptor/ligand interactions, production of IGFBPs by breast cancer cells could alter their IGF-depend