Insulin-like growth factors and breast cancer
โ Scribed by AV Lee; D Yee
- Book ID
- 116152546
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 712 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0753-3322
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๐ SIMILAR VOLUMES
In the current study the authors have investigated whether human primary breast cancer specimens contain insulin-like growth factor-1 (IGF-1) receptors (IGF-1-R) or IGF-1-like activities. Simultaneously, epidermal growth factor (EGF) receptors (EGF-R) and cytosolic estrogen receptor (ER), progestero
Insulin-like growth factor-I (IGF-I) has mitogenic and antiapoptotic effects on breast cancer cells. Epidemiologic studies have shown that high plasma levels of IGF-I and low levels of IGF binding protein (BP)-3 are associated with increased risk of breast cancer in premenopausal women. The actions