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Insulin-like growth factors and breast cancer

โœ Scribed by AV Lee; D Yee


Book ID
116152546
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
712 KB
Volume
49
Category
Article
ISSN
0753-3322

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Insulin-like growth factor-I (IGF-I) has mitogenic and antiapoptotic effects on breast cancer cells. Epidemiologic studies have shown that high plasma levels of IGF-I and low levels of IGF binding protein (BP)-3 are associated with increased risk of breast cancer in premenopausal women. The actions