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Insulin-like growth factor binding proteins and breast cancer

โœ Scribed by Ashok Subramanian; Anup Sharma; Kefah Mokbel


Publisher
Springer US
Year
2007
Tongue
English
Weight
368 KB
Volume
107
Category
Article
ISSN
0167-6806

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## Abstract The insulinโ€like growth factors (IGFs) are potent mitogens for breast cancer cells and their activity is modulated by high affinity binding proteins (IGFBPs). We have recently shown that IGFBPโ€1 purified from human amniotic fluid neutralizes IGFโ€Iโ€dependent growth of MCFโ€7 cells. In thi