Insulin-like growth factor-I enhances choleretic action of FK506 in rats
β Scribed by M Mabuchi; I Kawamura; S Takeshita; M Fushimi; S Takakura; J Hirosumi; S Mutoh
- Book ID
- 117233422
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 69 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0041-1345
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The acute metabolic actions of insulin-like growth factor I were studied in anaesthetized adult rats and its potency was compared to that of insulin. Following an i.v. bolus injection of insulin-like growth factor I a dose-dependent decrease of blood glucose and serum non-esterified fatty acid conce
## Republic of Germany \* Insulinlike growth factor-I (IGF-I) is of critical importance in the regulation of tissue growth and cellular differentiation (1, 2). In addition to its growthpromoting effects, a rapid insulin-like metabolic activity (e.g., hypoglycemia after intravenous injection) has b