Insulin-like growth factor-I and new opportunities for cancer prevention
β Scribed by Jeff Holly
- Book ID
- 117298148
- Publisher
- The Lancet
- Year
- 1998
- Tongue
- English
- Weight
- 60 KB
- Volume
- 351
- Category
- Article
- ISSN
- 0140-6736
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π SIMILAR VOLUMES
Insulin-like growth factor-I (IGF-I) has mitogenic and antiapoptotic effects on breast cancer cells. Epidemiologic studies have shown that high plasma levels of IGF-I and low levels of IGF binding protein (BP)-3 are associated with increased risk of breast cancer in premenopausal women. The actions
Consideration of existing data regarding clinical and biochemical risk factors for the development of breast cancer leads to the hypothesis that enhanced insulin-like growth factor I (IGF-I) activity plays a significant role in the development of this disease. Abnormal IGF-l activity may be related