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Insulin-like growth factor binding protein-3, in association with IGF-1 receptor, can predict prognosis in squamous cell carcinoma of the head and neck

✍ Scribed by Jong-Mu Sun; Hyun Jung Jun; Young Hyeh Ko; Yeon Hee Park; Yong Chan Ahn; Young-Ik Son; Jeong-Hwan Baek; Keunchil Park; Myung-Ju Ahn

Book ID: 113833554
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 704 KB
Volume: 47
Category: Article
ISSN: 1368-8375
DOI: 10.1016/j.oraloncology.2011.06.007

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Insulin-like growth factor binding protein (IGFBP)-3 effects proliferation and differentiation of numerous cell types by binding to insulin-like growth factors (IGF) and attenuating their activity or by directly affecting cells in an IGFindependent manner. Consequently, IGFBPs produced by specific c