Insulin inhibits its own secretion from isolated, perifused human pancreatic islets
โ Scribed by P. Marchetti; D. W. Scharp; M. McLear; E. H. Finke; B. Olack; C. Swanson; R. Giannarelli; R. Navalesi; P. E. Lacy
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 361 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0940-5429
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๐ SIMILAR VOLUMES
A mathematical insulin-secretion model was constructed by analyzing the glucose-induced insulin secretion using a control theory. To validate the model, experimental data obtained in the isolated rat pancreatic islet perifusion system were compared with the simulation results. The simulation study o
Human islets of Langerhans were isolated from the pancreas removed from a 13-year-old female transplant donor. The islets were incubated in a culture medium for 24 h in the presence of human lymphoblastoid interferon (1000 units/ml). Insulin secretion, proinsulin biosynthesis, total protein biosynth