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Insulin inhibition of endothelial prostacyclin production

✍ Scribed by Ronnie A. Rosenthal; Victor H. Ocasio

Book ID: 116010534
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 555 KB
Volume: 49
Category: Article
ISSN: 0022-4804
DOI: 10.1016/0022-4804(90)90028-z

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## Abstract To understand the role of prostacyclin (PGI~2~) in protecting endothelial cells from apoptosis, we evaluated the effects of carbaprostacyclin (cPGI~2~) on H~2~O~2~‐induced human umbilical vein endothelial cell (HUVEC) apoptosis. cPGI~2~ suppressed H~2~O~2~‐induced annexin V‐positive cel