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Cyclosporine inhibits endothelial cell prostacyclin production

✍ Scribed by Ronnie A. Rosenthal; Nonyelu A. Chukwuogo; Victor H. Ocasio; Kim U. Kahng

Book ID
116010369
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
430 KB
Volume
46
Category
Article
ISSN
0022-4804

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## Abstract To understand the role of prostacyclin (PGI~2~) in protecting endothelial cells from apoptosis, we evaluated the effects of carbaprostacyclin (cPGI~2~) on H~2~O~2~‐induced human umbilical vein endothelial cell (HUVEC) apoptosis. cPGI~2~ suppressed H~2~O~2~‐induced annexin V‐positive cel