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Insulin induces neurite outgrowth via SIRT1 in SH-SY5Y cells

✍ Scribed by Liu, Y.; Yao, Z.; Zhang, L.; Zhu, H.; Deng, W.; Qin, C.

Book ID
120049894
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
936 KB
Volume
238
Category
Article
ISSN
0306-4522

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Exogenously added gangliosides are known to promote neurite outgrowth in a variety of cell types, including some neuroblastoma cell lines. To study neuritogenesis in SH-SY5Y human neuroblastoma we serum starved the cells for 24 hr and exposed them to gangliosides (GM1, GM3, or GT1b), platelet-derive