Exogenously added gangliosides are known to promote neurite outgrowth in a variety of cell types, including some neuroblastoma cell lines. To study neuritogenesis in SH-SY5Y human neuroblastoma we serum starved the cells for 24 hr and exposed them to gangliosides (GM1, GM3, or GT1b), platelet-derive
✦ LIBER ✦
PPARγ stimulation promotes neurite outgrowth in SH-SY5Y human neuroblastoma cells
✍ Scribed by Gianluca Miglio; Lorenza Rattazzi; Arianna C. Rosa; Roberto Fantozzi
- Book ID
- 116771249
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 797 KB
- Volume
- 454
- Category
- Article
- ISSN
- 0304-3940
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## Abstract Neuroblastomas are pediatric tumors originating from immature neuroblasts in the developing peripheral nervous system. Differentiation therapies could help lowering the high mortality due to rapid tumor progression to advanced stages. Oleic acid has been demonstrated to promote neuronal