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Insulin-Induced Cell Cycle Progression Is Impaired in Chinese Hamster Ovary Cells Overexpressing Insulin Receptor Substrate-3

✍ Scribed by Kaburagi, Yasushi; Yamashita, Ryo; Ito, Yuzuru; Okochi, Hitoshi; Yamamoto-Honda, Ritsuko; Yasuda, Kazuki; Sekihara, Hisahiko; Sasazuki, Takehiko; Kadowaki, Takashi; Yazaki, Yoshio

Book ID
126846079
Publisher
Endocrine Society
Year
2004
Tongue
English
Weight
733 KB
Volume
145
Category
Article
ISSN
0013-7227

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Gene 33 (g33) is a non-tissue-specific gene regulated in rat liver and hepatoma cells by insulin and other agents. It is thought to participate in the transition from quiescence to proliferation in mitogen-treated cells. The mechanism(s) by which insulin exerts its action on g33 are not totally unde