✦ LIBER ✦

Insulin binding and action in isolated rat hepatocytes: Evidence for spare receptors

✍ Scribed by H.J.L. Frank; M.B. Davidson; P.A. Serbin

Book ID: 118948276
Publisher: Elsevier Science
Year: 1981
Tongue: English
Weight: 704 KB
Volume: 30
Category: Article
ISSN: 1532-8600
DOI: 10.1016/0026-0495(81)90035-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Hepatocyte insulin binding and action in

Hepatocyte insulin binding and action in rats with sommatomammotrophic tumours

✍ M. B. Davidson; S. Melmed 📂 Article 📅 1983 🏛 Springer 🌐 English ⚖ 693 KB

The effects of chronic elevations of growth hormone levels on hepatic insulin binding and action were studied in rats with subcutaneously implanted growth hormone-producing tumours. These animals were significantly heavier (p less than 0.001; 388 +/- 29 versus 239 +/- 4 g), had elevated insulin leve

Acute effects of insulin on surface insu

Acute effects of insulin on surface insulin receptors in isolated hepatocytes. Evidence for a recycling pathway

✍ Anne M. Bonser; Peter Garcia-Webb 📂 Article 📅 1984 🏛 Elsevier Science 🌐 English ⚖ 296 KB

Insulin binding and degradation in isola

Insulin binding and degradation in isolated hepatocytes from streptozotocin injected rats

✍ Peter Garcia-Webb; Anne M. Bonser 📂 Article 📅 1985 🏛 Elsevier Science 🌐 English ⚖ 408 KB

Effects of phorbol esters on insulin rec

Effects of phorbol esters on insulin receptor function and insulin action in hepatocytes: evidence for heterogeneity

✍ José F. Caro; Michelle Jenquin; Stuart Long 📂 Article 📅 1992 🏛 Springer 🌐 English ⚖ 320 KB

We investigated the effect of phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator on insulin receptors and insulin action in freshly isolated and primary cultures of rat hepatocytes. PMA (1 x 10(-7) M) did not alter insulin receptor numbers or affinity either acutely or chronic

Mechanisms of the fasting-induced dissoc

Mechanisms of the fasting-induced dissociation of insulin binding from its action in isolated rat hepatocytes

✍ Michael Trowbridge; Ann Sussman; Linda Ferguson; Boris Draznin; Naomi Neufeld; N 📂 Article 📅 1984 🏛 Springer 🌐 English ⚖ 863 KB

Fasting leads to an increase in insulin binding to isolated rat hepatocytes from 12 to 17%. This increase was accounted for by changes in the affinity of insulin receptors without alteration in their number. In contrast, the responsiveness of hepatocytes to insulin was markedly diminished in fasted

The effects of fasting on glucagon bindi

The effects of fasting on glucagon binding and action in isolated rat hepatocytes

✍ JoséF. Caro; John M. Amatruda 📂 Article 📅 1980 🏛 Elsevier Science 🌐 English ⚖ 704 KB