Effects of phorbol esters on insulin rec
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JosΓ© F. Caro; Michelle Jenquin; Stuart Long
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Article
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1992
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Springer
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English
β 320 KB
We investigated the effect of phorbol 12-myristate 13-acetate (PMA), a protein kinase C (PKC) activator on insulin receptors and insulin action in freshly isolated and primary cultures of rat hepatocytes. PMA (1 x 10(-7) M) did not alter insulin receptor numbers or affinity either acutely or chronic