Insulin and Insulin-like Growth Factor-I Promote Rabbit Blastocyst Development and Prevent Apoptosis
β Scribed by Herrler, A.
- Book ID
- 125850302
- Publisher
- Society for the Study of Reproduction
- Year
- 1998
- Tongue
- English
- Weight
- 274 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0006-3363
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Insulin-like growth factor-I (IGF-NGF withdrawal. The antiapoptotic effect of IGF-I I) is emerging as an important growth factor able to was completely blocked by LY294002, an inhibitor of modulate the programmed cell death (PCD) pathway mediated by the cysteine-dependent aspartate prote-PI 3-kinase
Both neurons and glia succumb to programmed cell death (PCD) when deprived of growth factors at critical periods in development or following injury. Insulin-like growth factor-I (IGF-I) prevents apoptosis in neurons in vitro. To investigate whether IGF-I can protect Schwann cells (SC) from apoptosis