Insulin and glucagon binding and stimulation of amino acid transport in isolated hepatocytes from streptozotocin diabetic rats
β Scribed by Michel Samson; Max Fehlmann; Odette Morin; Jacqueline Dolais-Kitabgi; Pierre Freychet
- Book ID
- 118948464
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 781 KB
- Volume
- 31
- Category
- Article
- ISSN
- 1532-8600
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The present report shows that System A-mediated 2-aminoisobutyric acid (AIB) uptake is elevated in hepatocytes isolated from adrenalectomized rats when they are compared to control cells. Although System ASC activity also shows this perturbation, Systems N, p, L1, and L2 are unaffected. Transport of
The effects of glucagon on amino acid transport in rat hepatocytes are not fully understood. We examined the effect of this hormone on alanine, serine and cysteine preferring system (system ASC)βmediated amino acid transport in rat hepatocyte monolayers using 2βaminoisobutyric acid (AIB) and L βcyst