Instant therapy of acquired agranulocytosis and sepsis by recombinant granulocyte-macrophage colony-stimulating factor in a polytrauma patient
β Scribed by Gross-Weege, W. ;Weiss, M. ;Wernet, P. ;Varney, M. ;Becker, H.
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 358 KB
- Volume
- 71
- Category
- Article
- ISSN
- 1432-1440
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A therapeutic trial of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) was attempted in a patient with neutropenia and frequent infections secondary to T-y lymphoproliferative disease (T-y LPD). During the 14 days of subcutaneous rhGM-CSF (500 kg/m2/day), the absolute e
Neutrophils (PMN) are the major host defence cells protecting the body against invasion by microorganisms. Products of oxidative metabolism mediate PMN microbicidal and tumoricidal activity, but the mechanisms by which these pathways become activated are not well understood. The colony stimulating f