Insights into the Branched-Chain Formati
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Huawei Chen; Zongbao Zhao; Tina M. Hallis; Zhihong Guo; Hung-wen Liu
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Article
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2001
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John Wiley and Sons
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English
โ 101 KB
A C-methyltransferase involved in methyl-branch formation in sugars has been characterized for the first time. TylC3, an (S)-adenosylmethylthionine(AdoMet)-dependent enzyme, catalyzes the attachment of a methyl branch [Eq. (1)] in the biosynthesis of L-mycarose, an unusual sugar found in tylosin and