Modeling the 3D structure of GPCRs from
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Sharon Shacham; Maya Topf; Noa Avisar; Fabian Glaser; Yael Marantz; Shay Bar-Hai
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Article
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2001
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John Wiley and Sons
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English
⚖ 377 KB
👁 1 views
## Abstract G‐protein‐coupled receptors (GPCRs) are a large and functionally diverse protein superfamily, which form a seven transmembrane (TM) helices bundle with alternating extra‐cellular and intracellular loops. GPCRs are considered to be one of the most important groups of drug targets because