## Abstract Gβproteinβcoupled receptors (GPCRs) are a large and functionally diverse protein superfamily, which form a seven transmembrane (TM) helices bundle with alternating extraβcellular and intracellular loops. GPCRs are considered to be one of the most important groups of drug targets because
ChemInform Abstract: Modeling the 3D Structure of GPCRs from Sequence
β Scribed by Sharon Shacham; Maya Topf; Noa Avisar; Fabian Glaser; Yael Marantz; Shay Bar-Haim; Silvia Noiman; Zvi Naor; Oren M. Becker
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 25 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
During a blind protein structure prediction experiment (the third round of the Critical Assessment of Techniques for Protein Structure Prediction; URL http://PredictionCenter.llnl.gov/ casp3/), four target proteins, T0047, T0048, T0055, and T0070, were modeled by comparison. These proteins display 6