The genes TSC1 and TSC2, encoding hamartin and tuberin, respectively, have been shown to be involved in the development of the autosomal dominantly inherited tumor syndrome tuberous sclerosis (TSC). However, inactivation of these genes has also been demonstrated to be associated with sporadic bladde
β¦ LIBER β¦
Insights from clinical studies into the role of the MLL gene in infant and childhood leukemia
β Scribed by Tanzina Chowdhury; Hugh J.M. Brady
- Book ID
- 116304441
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 195 KB
- Volume
- 40
- Category
- Article
- ISSN
- 1079-9796
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## Abstract Here we report the case of a 7βmonthβold boy who presented with biphenotypic acute leukemia, but with leukemia cells of Bβcell phenotype present at the time of relapse. Two cell lines were derived from bone marrow specimens obtained at relapse, and immunophenotyping and analysis of anti