Insights into cancer from transgenic mou
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Macleod, Kay F.; Jacks, Tyler
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Article
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1999
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John Wiley and Sons
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English
β 391 KB
π 2 views
The generation of mice designed to overexpress activated forms of oncogenes or carrying targeted mutations in tumour suppressor genes, has allowed scientists to causally link the function of these genes with specific tumour processes, such as proliferation, apoptosis, angiogenesis or metastasis. In