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Insight into the High Duplex Stability of the Simplified Nucleic Acid GNA

✍ Scribed by Mark K. Schlegel; Xiulan Xie; Lilu Zhang; Eric Meggers

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
535 KB
Volume
121
Category
Article
ISSN
0044-8249

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Mutagen–nucleic acid complexes at the polynucleotide duplex level in solution: Intercalation of proflavine into poly(dA-dT) and the melting transition of the complex
✍ Dinshaw J. Patel 📂 Article 📅 1977 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 763 KB

## Abstract The nmr chemical shifts and line widths of the nucleic acid base and sugar proton resonances and the proflavine ring protons can be monitored through the melting transition of the proflavine + poly(dA‐dT) complex, phosphate/dye (__P__/__D__) ratio = 24 and 8 in 1__M__ salt solution. The