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An Approach to Predicting the Stabilities of Peptide Nucleic Acid:DNA Duplexes

✍ Scribed by Timothy J. Griffin; Lloyd M. Smith


Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
138 KB
Volume
260
Category
Article
ISSN
0003-2697

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## Abstract High‐resolution NMR studies of an α‐homo‐DNA:RNA duplex reveal the formation of a right‐handed parallel‐oriented helix. It differs significantly from a standard A‐ or B‐type helix by a small twist value (26.2Β°), which leads to a helical pitch of 13.7 base pairs per helical turn, a negat