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Inside Cover: Stable, Non-Destructive Immobilization of Native Nuclear Membranes to Micro-Structured PDMS for Single-Molecule Force Spectroscopy (ChemPhysChem 9-10/2009)

✍ Scribed by Martina Rangl; Reinat Nevo; Ivan Liashkovich; Victor Shahin; Ziv Reich; Andreas Ebner; Peter Hinterdorfer


Book ID
102120206
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
390 KB
Volume
10
Category
Article
ISSN
1439-4235

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✦ Synopsis


Abstract

The investigation of native nuclear pore complexes (NPCs) with single‐molecule force spectroscopy requires stable and non‐destructive attachment of the nuclear envelope. Modified, micro‐structured PDMS turns out to be perfectly suited for membrane preparation as it preserves structure and function of the entire NPC, as shown on p. 1553 by A. Ebner et al.magnified image


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