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Inositol 1,4,5-trisphosphate receptor isoform expression in mouse pancreatic islets: effects of carbachol

✍ Scribed by Bumsup Lee; Suzanne G. Laychock

Book ID
113992532
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
819 KB
Volume
61
Category
Article
ISSN
0006-2952

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## Abstract Inositol 1,4,5‐trisphosphate receptors (IP~3~R) are ligand‐gated intracellular Ca^2+^channels that mediate release of Ca^2+^ from intracellular stores into the cytosol on activation by second messenger IP~3~. Similarly, IP~3~R mediated changes in cytosolic Ca^2+^ concentrations control