Distribution of inositol 1,4,5-trisphosphate receptor mRNA in mouse tissues
β Scribed by Teiichi Furuichi; Chiyo Shiota; Katsuhiko Mikoshiba
- Book ID
- 115923156
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 733 KB
- Volume
- 267
- Category
- Article
- ISSN
- 0014-5793
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Inositol 1,4,5βtrisphosphate receptors (IP~3~R) are ligandβgated intracellular Ca^2+^channels that mediate release of Ca^2+^ from intracellular stores into the cytosol on activation by second messenger IP~3~. Similarly, IP~3~R mediated changes in cytosolic Ca^2+^ concentrations control
## Abstract At the time of fertilization, an increase in the intracellular Ca^2+^ concentration ([Ca^2+^]~i~) underlies egg activation and initiation of development in all species studied to date. The inositol 1,4,5βtrisphosphate receptor (IP~3~R1), which is mostly located in the endoplasmic reticu