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Inositol 1,4,5-trisphosphate generation and calcium mobilisation via activation of an atypical P2 receptor in the neuronal cell line, N1E-115

โœ Scribed by Philip A. Iredale; Keith F. Martin; Stephen P.H. Alexander; Stephen J. Hill; David A. Kendall

Book ID
117959682
Publisher
Nature Publishing Group
Year
1992
Tongue
English
Weight
978 KB
Volume
107
Category
Article
ISSN
0007-1188

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โœ Robert A. Wilcox; Stefan R. Nahorski; Deborah A. Sawyer; Changsheng Liu; Barry V ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 707 KB

The functional significance of the 2- and 3-hydroxyl groups of 1 D-myo-inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] was probed by using Ins(1,4,5)P3 analogues variously modified at positions 2 and 3 or elsewhere. The intrinsic activities of these compounds were compared to that of Ins(1,4,5)P3, using