✦ LIBER ✦

Innentitelbild: Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D (Angew. Chem. 23/2007)

✍ Scribed by Regina M. Kanada; Daisuke Itoh; Mitsuo Nagai; Jun Niijima; Naoki Asai; Yoshiharu Mizui; Shinya Abe; Yoshihiko Kotake

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 39 KB
Volume: 119
Category: Article
ISSN: 0044-8249
DOI: 10.1002/ange.200790103

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Inside Cover: Total Synthesis of the Pot

Inside Cover: Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D (Angew. Chem. Int. Ed. 23/2007)

✍ Regina M. Kanada; Daisuke Itoh; Mitsuo Nagai; Jun Niijima; Naoki Asai; Yoshiharu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 39 KB 👁 2 views

Total Synthesis of the Potent Antitumor

Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D

✍ Regina M. Kanada; Daisuke Itoh; Mitsuo Nagai; Jun Niijima; Naoki Asai; Yoshiharu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 158 KB 👁 2 views

Total Synthesis of the Potent Antitumor

Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D

✍ Regina M. Kanada; Daisuke Itoh; Mitsuo Nagai; Jun Niijima; Naoki Asai; Yoshiharu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 157 KB 👁 1 views

Total Synthesis of the Potent Antitumor

Total Synthesis of the Potent Antitumor Macrolides Pladienolide B and D

✍ Regina M. Kanada; Daisuke Itoh; Mitsuo Nagai; Jun Niijima; Naoki Asai; Yoshiharu 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 210 KB 👁 1 views

Die Autoren dieser Zuschrift möchten das

Titelbild: Total Synthesis and Antitumor

Titelbild: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. 47/2006)

✍ Ulrich Klar; Bernd Buchmann; Wolfgang Schwede; Werner Skuballa; Jens Hoffmann; R 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB 👁 1 views

Cover Picture: Total Synthesis and Antit

Cover Picture: Total Synthesis and Antitumor Activity of ZK-EPO: The First Fully Synthetic Epothilone in Clinical Development (Angew. Chem. Int. Ed. 47/2006)

✍ Ulrich Klar; Bernd Buchmann; Wolfgang Schwede; Werner Skuballa; Jens Hoffmann; R 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 161 KB

**__Nature is a brilliant architect__** for the design of compounds with interesting biological functions. Epothilone B (top), a metabolite of myxobacteria (fruiting body in background), served as the lead structure for the development of an anticancer drug candidate. Optimization efforts led to ZK‐