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Innate immunity: Antigen recognition: Web Alert

โœ Scribed by David R Greaves

Book ID
104359022
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
29 KB
Volume
12
Category
Article
ISSN
0952-7915

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โœฆ Synopsis

Innate immunity

The innate immune response is the first line of defence against pathogens. Phagocyte recognition and uptake of pathogens involves pattern-recognition molecules such as the macrophage mannose receptor, scavenger receptors and a recently identified family of molecules, the Toll-like receptors. Genetic diseases that result in a defective innate immune response include chronic granulomatous disease (CGD) and leukocyte adhesion deficiency (LAD).

Understanding the Immune System http://www.mfmdesign.com

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Innate immunity Antigen recognition Web
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โœ DavidR Greaves ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 78 KB

## Innate immunity Innate (or nonadaptive) immune responses to pathogens are less specific but no less important than classical T-cell and B-cell responses to pathogens. The key cellular players in the innate immune system are the macrophages and neutrophils which are the professional phagocytes.

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## Immunity to infection There are few Web sites dealing specifically with the immune response to pathogens but there are Web sites devoted to most of the major pathogens. Some of the best sites are listed below. 'The DNA Vaccine Web' http :l lwww.genweb.comlDnavaxl dnavax.html A good source of in