Initiation of blood coagulation: the tis
โ
Daniel Kirchhofer; Yale Nemerson
๐
Article
๐
1996
๐
Elsevier Science
๐
English
โ 637 KB
Tissue factor (TF), a transmembrane glycoprotein, functions as an essential activator of the serine protease factor Vlla. This enzymatic complex is considered to be the principal initiator of in vivo coagulation. Recent studies emphasize the role of the TF/Vlla complex in a number of pathophysiologi