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The Role of Hageman Factor in the Initiation of Blood Coagulation

✍ Scribed by R. M. Hardisty; J. Margolis

Book ID
117946007
Publisher
John Wiley and Sons
Year
1959
Tongue
English
Weight
495 KB
Volume
5
Category
Article
ISSN
0007-1048

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Tissue factor (TF), a transmembrane glycoprotein, functions as an essential activator of the serine protease factor Vlla. This enzymatic complex is considered to be the principal initiator of in vivo coagulation. Recent studies emphasize the role of the TF/Vlla complex in a number of pathophysiologi