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Initial temporal field defect in Leber hereditary optic neuropathy

✍ Scribed by Masato Wakakura; Waki Fujie; Yuko Emoto


Book ID
106327677
Publisher
Springer
Year
2009
Tongue
English
Weight
325 KB
Volume
53
Category
Article
ISSN
0021-5155

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## Abstract Leber hereditary optic neuropathy (LHON) is a mitochondrial disease characterized by visual loss resulting from retinal ganglion cell degeneration. Despite the important role of respiratory chain deficiency and oxidative stress induced by mtDNA point mutations affecting complex I, excit