Inhibitory effects of phenylpropanoid metabolites on copper-induced protein oxidative modification of mice brain homogenate, in vitro
β Scribed by Shizuo Toda
- Book ID
- 111636194
- Publisher
- Humana Press Inc
- Year
- 2002
- Tongue
- English
- Weight
- 91 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0163-4984
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Ougi-Keishi-gomotsu-to a traditional herbal medicine, is used clinically for patients with abnormal sensations and pain in the legs in neuropathy. It was shown to have inhibitory effects on lipid peroxidation and protein oxidative modification of brain homogenate induced by copper. Its effect was st
## Background: The cyclooxygenase-2 inhibitor nimesulide is able to reduce kainate-induced oxidative stress in vivo. here we investigate if this effect is mediated by the direct antioxidant properties of nimesulide using a well-characterized in vitro model of kainate toxicity. ## Results: Exposur