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Inhibitory effects of crocetin on high glucose-induced apoptosis in cultured human umbilical vein endothelial cells and its mechanism

โœ Scribed by Lingdong Meng; Lianqun Cui


Book ID
107641765
Publisher
Springer
Year
2008
Tongue
English
Weight
370 KB
Volume
31
Category
Article
ISSN
0253-6269

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## Abstract Hyperglycemia and elevation of methylglyoxal (MG) are symptoms of diabetes mellitus (DM). We previously showed that high glucose (HG; 30 mM) or MG (50โ€“400 ยตM) could induce apoptosis in mammalian cells, but these doses are higher than the physiological concentrations of glucose and MG in