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Inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 reverse transcriptase, protease and integrase

✍ Scribed by T.B. Ng; T.K. Au; T.L. Lam; X.Y. Ye; D.C.C. Wan


Book ID
117173316
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
158 KB
Volume
70
Category
Article
ISSN
0024-3205

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By bioactive-guided fractionation of a water extract of Cordia spinescens, magnesium lithospermate (1), calcium rosmarinate (2) and magnesium rosmarinate (3) were isolated as potent inhibitory substances against HIV-1 reverse transcriptase (RT) with IC 50 values of 0.8, 5.8 and 3.1 M, respectively.