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Inhibitory effect of prostaglandin (PG) D2, PGJ2 and Δ12-PGJ2 on proliferation of cells involved in host defense

✍ Scribed by C. Haberl; F. Flügel; S. Geuenich; L. Hültner; M. Falk; W. Wilmanns; C. Denzlinger


Book ID
117665611
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
124 KB
Volume
33
Category
Article
ISSN
0959-8049

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Cyclopentenone prostaglandins (PGs) such as delta 12-PGJ2 and PGA are potent inducers of growth inhibition in a variety of cultured cells, including epidermal cells. These PGs are actively transported into cells by a specific carrier on cell membrane and accumulate in cell nuclei with binding to nuc