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Effect of a cytotoxic prostaglandin, Δ12-PGJ2 on the cytoskeleton and E-cadherin expression in transformed epidermal cells in culture

✍ Scribed by Ikai, Kouichi; Yamamoto, Masamitsu; Matsuyoshi, Norihisa; Fukushima, Masanori


Book ID
123272874
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
160 KB
Volume
6
Category
Article
ISSN
0923-1811

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Effects of cytotoxic prostaglandin, Δ12P
✍ K. Ikai; M. Fukushima 📂 Article 📅 1990 🏛 Springer-Verlag 🌐 English ⚖ 821 KB

Cyclopentenone prostaglandins (PGs) such as delta 12-PGJ2 and PGA are potent inducers of growth inhibition in a variety of cultured cells, including epidermal cells. These PGs are actively transported into cells by a specific carrier on cell membrane and accumulate in cell nuclei with binding to nuc