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Inhibitory effect of nitric oxide on the metabolism of halogenated volatile anesthetics by cytochrome P-450

✍ Scribed by Eiji Masaki


Publisher
Springer
Year
1999
Tongue
English
Weight
110 KB
Volume
13
Category
Article
ISSN
0913-8668

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A theoretical study on the oxidative met
✍ L. M. H. Koymans; W. M. P. B. Menge; G. M. DonnΓ©-Op Den Kelder; J. M. Te Koppele πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 450 KB

## Abstract The oxidative metabolism of 4‐chloroacetanilide (4‐ClAA, 1) by cytochrome P450 has been studied theoretically using __ab‐initio__ energy and spin‐distribution calculations. A mechanism of oxidation for 4‐ClAA is proposed which is in accordance with recent views on the mechanism of metab