Inhibitory Effect of New Pyrimidine Bases on Trypanosoma Cruzi
โ Scribed by A. M. Gonzalez; S. Castanys; A. Osuna; M. M. Herrador; J. F. Dominguez
- Publisher
- John Wiley and Sons
- Year
- 1989
- Tongue
- English
- Weight
- 209 KB
- Volume
- 322
- Category
- Article
- ISSN
- 0365-6233
No coin nor oath required. For personal study only.
โฆ Synopsis
Nine analogues of pyrimidine bases have been tested in vitro, using cultures Ein Hemmeffekt neuer Pyrimidin-Basen gegen T~y~anosonia cnrd of epimtigote forms of Trypanosoma cruzi: Three of them are inhibitors of the normal development of Tryjmnosoma cruzi.
๐ SIMILAR VOLUMES
The Trypanosoma cruzi membrane glycoprotein AGC10 has been shown to alter some human macrophage functions (De Diego, J. L. et al., J. Immunol. 1997. 159: 4983-4989). We show here that, in the presence of AGC10, [ 3 H]thymidine incorporation by normal human lymphocytes stimulated with anti-CD3 or phy
The tautomerism of pyrimidine bases was applied to a new type of polymer synthesis that was achieved by the dehydrochlorination of dichloropyrimidines with diols to give polyethers containing a 2,4-pyrimidine structure in the main chain. The polymer decomposed to uracil or thymine under an acidic co