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Inhibitory Effect of Methanol Extracts from Edible Mushroom on TPA-induced Ear Oedema and Tumour Promotion in Mouse Skin

✍ Scribed by Ken Yasukawa; Hiroshi Kanno; Tomohiro Kaminaga; Michio Takido; Yoshimasa Kasahara; Kunio Kumaki

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 208 KB
Volume: 10
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199606)10:4<367::aid-ptr852>3.0.co;2-d

No coin nor oath required. For personal study only.

✦ Synopsis

Edible mushroom extracts inhibited 12-0-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema in mice. 'henty seven methanol extracts obtained from mushrooms were assayed and their inhibition ratios calculated. The methanol extracts of Russula delica, Mycoleptodonoides aitchisonii, Lactarius deliciosus, Naematoloma sublateritium, Lyophyllum decastes and Lyophyllum connatum markedly inhibited the inllammatory activity induced by TPA in mice. The methanol extract from Mycoleptodonoides aitchisoni was found to inhibit tumour promotion in two-stage carcinogenesis in mouse skin.

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