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Inhibitory Effect of Carnosolic Acid on HIV-1 Protease in Cell-Free Assays

✍ Scribed by Pariš, A.; Štrukelj, B.; Renko, M.; Turk, V.; Pukl, M.; Umek, A.; Korant, B. D.


Book ID
126709642
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
355 KB
Volume
56
Category
Article
ISSN
0163-3864

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Forty-eight methanol and aqueous extracts from Sudanese plants were screened for their inhibitory activity on viral replication. Nineteen extracts showed inhibitory effects on HIV-induced cytopathic effects (CPE) on MT-4 cells. The extracts were further screened against HIV-1 protease (PR) using an