Inhibitory effect of berberine ontert-butyl hydroperoxide-induced oxidative damage in rat liver
โ Scribed by Jin-Ming Hwang; Chau-Jong Wang; Feu-Pi Chou; Tsui-Hwa Tseng; Yih-Shou Hsieh; Wea-Lung Lin; Chia-Yih Chu
- Publisher
- Springer-Verlag
- Year
- 2002
- Tongue
- English
- Weight
- 518 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0340-5761
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๐ SIMILAR VOLUMES
Boldine, an aporphine alkaloid, was recently shown by us to exhibit potent antioxidant properties. We report here that boldine concentration-dependently inhibited the peroxidative (accumulation of thiobarbituric acid reactive substances) and lytic damage (trypan blue exclusion and lactate dehydrogen
## Abstract The hepatotoxic and lipid peroxidative potentials of __t__โbutyl hydroperoxide (__t__โBuOOH) towards isolated perfused rat livers were investigated at doses of 1 and 3 mmol I^โ1^. __t__โBuOOH led to a concentrationโdependent release of cytosolic (glutamateโpyruvate transaminase and lact